Professor

Phone: (027)83692733

Email: wkpzcq@163.com

Academic Areas: PhD in Tongji Medical College of Pharmacy, 2007, Wuhan, China.

Research Interests: Bioactivity, structures and new formulations of polysaccharide.

Professional Experience

Professor (2010-present); Department of Pharmacy, HUST

Associate Professor (2002-2010); Department of Pharmacy, HUST

Lecture (1997-2002); Department of Pharmacy, HUST

Selected Publications

  • 1. Jinglin Wang, Weiyong Li, Xiao Huang, Ying Liu, Qiang Li, Ziming Zheng, Kaiping Wang*: A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice.oncotarget, 2016.
  • 2. Kaiping Wang, Zhuohong Tang, Ziming Zheng, Peng Cao, Weizhi Shui, Qiang Li and Yu Zhang*: Protective effects of Angelica sinensis polysaccharide against hyperglycemia and liver injury in multiple low-dose streptozotocininduced type 2 diabetic BALB/c mice. Food &Function.2016.
  • 3. Kaiping Wang, Peng Cao, Hanxiang Wang, Zhuohong Tang, Na Wang, Jinglin Wang & Yu Zhang*: Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci. Rep. 2016,6:26229
  • 4. Yu Zhang , Qiang Li , Junfeng Wang , Fang Cheng , Xiao Huang , Yao Cheng , Kaiping Wang*: Polysaccharide from Lentinus edodes combined with oxaliplatin possesses the synergy and attenuation effect in hepatocellular carcinoma, cancer letters. 2016,377:117-125
  • 5. Yu Zhang , Tao Zhou , Hongjing Wang , Zheng Cui , Fang Cheng , Kai-ping Wang*: Structural characterization and in vitro antitumor activity of an acidic polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydrate Polymers. 2016,147:401-408.
  • 6. Yao Cheng, Jiali Zhou, Qiang Li, Ying Liu, Kaiping Wang* ,Yu Zhang*: The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice. Food & Function. 2016,7:1033-1039.
  • 7. Kaiping Wang , Zhizhen Song , Hongjing Wang , Qiang Li , Zheng Cui , Yu Zhang*: Angelica sinensis polysaccharide attenuates concanavalin A-induced liver injury in mice. International Immunopharmacology. 2016,31:140-148.
  • 8. Yu Zhang, Qiang Li, Yamin Shu, Hongjing Wang , Ziming Zheng, Jinglin Wang, Kaiping Wang*: Induction of apoptosis in S180 tumour bearing mice by polysaccharide from Lentinus edodes via mitochondria apoptotic pathway. Journal of functional foods. 2015,15:151-159.
  • 9. Kaiping Wang, Peng Cao, Wezhi Shui, Qiuxiang Yang, Zhuohong Tang, Yu Zhang*: Angelica sinensis polysaccharide regulates glucose and lipid metabolism disorder in prediabetic and streptozotocin-induced diabetic mice through the elevation of glycogen levels and reduction of inflammatory factors. Food & Function. 2015,6:902-909.
  • 10. Yu Zhang, Yao Cheng, Na Wang, Qilin Zhang, Kaiping Wang*: The action of JAK, SMAD and ERK signal pathways on hepcidin suppression by polysaccharides from Angelica sinensis in rats with iron deficiency anemia. Food & Function,2014,5:1381-1388.
  • 11. Kaiping Wang, Jun Wang, Qiang Li, Qilin Zhang, Ruxu You, Yao Cheng, Li Luo, Yu Zhang*: Structural differences and conformational characterization of five bioactive polysaccharides from Lentinus Edodes. Food Research International, 2014,62:223-232.
  • 12.Ruxu You, Jinyu Liu, Shijun Li, Liu Wang, Kaiping Wang*, Yu Zhang*: Alkali-Soluble Polysaccharide, Isolated from Lentinus edodes, Induces Apoptosis and G2/M Cell Cycle Arrest in H22 Cells Through Microtubule Depolymerization. Phytotherapy Research,2014,12:1837-1845
  • 13. Kaiping Wang, Qilin Zhang, Ying Liu, Jun Wang, Yao Cheng, Yu Zhang*: Structure and inducing tumor cell apoptosis activity of polysaccharide isolated from Lentinus edodes. Journal of agricultural and food chemistry, 2013,61(41):9849-9858.
  • 14.Jinyu Liu, Yu Zhang, Ruxu You,Fang Zeng, Dan Guo, Kaiping Wang*: Polysaccharide Isolated from Angelica sinensis Inhibits Hepcidin Expression in Rats with Iron Deficiency Anemia. Journal Of Medical Food, 2012,15 (10):923–929.
  • 15. Yu Zhang, Mingming Li, Fang Zeng, Yao Cheng, Kaiping Wang*:Study to establish the role of JAK2 and SMAD1/5/8 pathways in the inhibition of hepcidin by polysaccharides from Angelica sinensis. Journal of Ethnopharmacology, 2012, 144(10):433-440.
  • 16.Liu Wang, Yu Zhang, Shijun Li, Yujuan Wang, Kaiping Wang*: Comparison of two kinds of magnetic nanoparticles in vivo and in vitro. J Huazhong Univ Sci Technol,2012,32(3) :444-450.
  • 17. Kaiping Wang, Fang Zeng, Jinyu Liu, Dan Guo, Yu Zhang*: Inhibitory effect of polysaccharides isolated from Angelica sinensis on hepcidin expression. Journal of Ethnopharmacology, 2011, 134(3):944-948.
  • 18. Ruxu You, Kaiping Wang, Jinyu Liu, Maochang Liu, Li Luo, Yu Zhang*: A comparison study between different molecular weight polysaccharides derived from Lentinus edodes and their antioxidant activities in vivo. Pharmaceutical Biology, 2011,49(12):1298-1305
  • 19. Yu Zhang, Ming Gu, Kaiping Wang*: Structure, Chain comformation and antitumor activity of a novel polysaccharide from Lentinus edodes. Fitoterapia, 2010, 81(8):1163-1170.
  • 20. Kaiping Wang, Zhixiang Chen: Studies on the Molecular Weight and Proposed Structure of the Angelica sinensis Polysaccharide-iron Complex[J]. Chinese Journal of Chemistry,2008,26(6):1-7.
  • 21. Peipei Wang, Yu Zhang, Kaiping Wang*: Effects of angelica sinensis polysaccharide-iron complex on hemolytic anemia and bone marrow injury in mice. Journal of Chinese Pharmaceutical Sciences,2008,(17):197-202.

                    22. Kaiping Wang: Preparation and Identification of Angelica sinensis Polysaccharide-iron Complex. Chemical Research in Chinese Universities,2005,21(6): 668-672.

Courses Taught

Physical Chemistry

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