Associate Professor

Phone: 027-83692745

Email: tansw@hust.edu.cn

Academic Areas: BioMedical Polymers

Research Interests: Synthesis of biocompatible/biodegradable polymers, design and application of stimuli-responsive drug delivery system

Academic Degrees

1. PhD in Polymer chemistry & physics, 2011, Zhejiang University, Hangzhou, China;

2. BEng in polymer science & engineering, 2005, Zhejiang University, Hangzhou, China.

Professional Experience

1. Lecturer (2013-present); Tongji School of Pharmacy, Huazhong University of Science & Technology

2. Postdoc (2011-2013); Tongji School of Pharmacy, Huazhong University of Science & Technology

Selected Publications

· 1.Bao YL, Yin MX, Hu XM, Zhuang XT, Sun Y, Guo YY, Tan SW*, Zhang ZP*. A Safe, Simple and Efficient Doxorubicin Prodrug Hybrid Micelle for Overcoming Tumor Multidrug Resistance and Targeting Delivery, Journal of Controlled Release, 2016, 235: 182-194; (co-responding author)

· 2.Tan SW, Wu TT, Zhang D and Zhang ZP*, Cell or cell membrane-based drug delivery systems, Theranostics, 2015,5(8): 863-881;

· 3.Bao YL, Guo YY, Zhuang XT, Li D, Cheng BL, Tan SW*, Zhang ZP*. Dα-Tocopherol Polyethylene Glycol Succinate-Based Redox-Sensitive Paclitaxel Prodrug for Overcoming Multidrug Resistance in Cancer Cells, Molecular Pharmaceutics, 2014,11(9): 3196-3209; (co-responding author)

· 4.Tan SW#, Sasada T#, Bershteyn A, et al. Combinational Delivery of Lipid-enveloped PLGA Nanoparticles Carrying Different Antigenic Epitopes for Induction of Anti-tumor immunity, Nanomedicine-UK, 2014, 9: 635-647; (#: equal contribution)

· 5.Zhao S#, Tan SW#, Guo YY, et al. pH-sensitive docetaxel-loaded TPGS-poly(β-amino ester) copolymer nanoparticles for overcoming multidrug resistance, Biomacromolecules, 2013, 14: 2636–2646; (#: equal contribution)

·  6.Yu YN#, Tan SW#, Zhao S, et al. Antitumor activity of docetaxel-loaded polymeric nanoparticles fabricated by SPG membrane emulsification technique, International Journal of Nanomedicine, 2013, 8:2641-2652; (#: equal contribution)

·  7.Tan SW, Li X, Guo YJ, et al. Lipid-Enveloped Hybrid Nanoparticles for Drug Delivery, Nanoscale, 2013, 5: 860-872;

·  8. Zhang ZP, Tan SW, Feng S-S, Vitamin E TPGS as a MolecuLar Biomaterial for Drug Delivery, Biomaterials, 2012, 33: 4889-4906;

·  9. Luo J, Huo F, Lin H, …, Tan SW*, Wang L-Q*. Stereochemical Heterogeneity of Biodegradable Poly(L-lactide) Homopolymer as Revealed by Temperature Rising Elution Fractionation and Successive Self-Nucleation/Annealing Thermal Fractionation, Journal of Polymer Science Part B: Polymer Physics, 2012, 50: 1277-1285; (co-responding author)

· 10. Zhao D, Tan SW, Yuan DQ, et al. Surface Functionalization of Porous Coordination Nanocages Via Click Chemistry and Their Application in Drug Delivery, Advanced Materials, 2011, 23: 90-93;

· 11. Tan SW, Zhao D, Yuan DQ, Wang HJ, Tu KH, Wang L-Q, Influence of Indomethacin-Loading on the Micellization of Thermosensitive Dextran-graft-poly(N-isopropylacrylamide) and the Drug Releasing, Reactive & Functional Polymers, 2011, 71: 820-827;

· 12. Tan SW, Wang HJ, Tu KH, Jiang HL, Wang L-Q, Ibuprofen Induced Drug Loaded Polymeric Micelles, Chinese Chemical Letters, 2011, 22: 1123-1126;

· 13. Tan SW, Han C, Wang HJ, et al. Preparation and Characterization of Thermo-Sensitive Mixed Micelles and in vitro Drug Release,Acta Polymerica Sinica,2011, 11: 1237-1243;

14.Hu HB, Yu L, Tan SW*, et al. Novel Complex Hydrogels based on N-Carboxyetheyl Chitosan and Quaternized Chitosan and Their Controlled in vitro Protein Release Property, Carbohydrate Research, 2010, 345, 462-468; (co-responding author) 

Courses Taught

*  1002301: Pharmaceutics

*  1002862: Pharmaceutics for Biologic Drugs

*  1413061: Polymers for Pharmaceutical Application

Project

  • 1. pH-, Reduction Dual-Sensitive Anticancer Drug-loaded Micelles with P-glycoprotein Inhibiting Activity (National Natural Science Foundation of China, 21204024, 2013-2015)
  • 2. Erythrocyte Membrane-enveloped Nanogel for Cancer Immunotherapy (China Postdoctoral Science Foundation, 2013T60722, 2013-2014)
  • 3. Multi-functional Hybrid Micelle for Overcoming MDR of Tumor (Fundamental Research Funds for the Central Universities, 2014QN134, 2014-2015)
  • 4. Smart Nanogel for Cancer Chemo-immunotherapy (Natural Science Foundation of Hubei Province, 2015CFB492, 2015-2016 )
  • 5. Study on Protein and Chemo Drug Co-loaded Delivery System with Programmed Drug Release Behavior (Fundamental Research Funds for the Central Universities, 2016YXMS138, 2016-2017)
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