Phone: 27-83692745


Academic Areas: Organic Chemistry, Medicinal Chemistry

Research Interests: Carbohydrate Chemistry, Free Radical Chemistry, Total Synthesis of Natural Products, Synthetic Methodology Development

Academic Degrees

Ph.D. in Organic Chemistry, 2004, Paris-Sud (XI) University, Orsay, France

M.S. in Organic Chemistry, 2000, Paris-Sud (XI) University, Orsay, France

B.S. in Chemistry, 1997, Central China Normal University, Wuhan, China

Professional Experience

Vice Dean (2014- present): School of Pharmacy, Huazhong University of Science and Technology

Professor (2012-present): School of Pharmacy, Huazhong University of Science and Technology

Scientist (2007-2012): Department of Medicinal Chemistry, Amgen Inc., Cambridge, MA, USA

Research Fellow (2004-2007): Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Selected Publications

1. Zeng, J.*; Sun, G.; Yao, W.; Zhu, Y.; Wang, R.; Cai, L.; Liu, K.; Zhang, Q.; Liu, X.; Wan, Q.* “3-Aminodeoxypyranoses in Glycosylation: Diversified Synthesis and Assembly in Oligosaccharides” Angew. Chem. Int. Ed. 2017, 56, DOI:10.1002/anie.201700178R1. (IF: 11.709)

2. Xiao, X.; Zhao, Y.; Shu, P.; Zhao, X.; Liu, Y.; Sun, J.; Zhang, Q.; Zeng, J.; Wan, Q.* “Remote Activation of Disarmed Thioglycosides in Latent-Active Glycosylation via Interrupted Pummerer Reaction”J. Am. Chem. Soc. 2016, 138, 13402. (IF: 13.038)

·Highlighted by X-MOL:

3. Shu, P.; Xiao, X.; Zhao, Y.; Tao, J.; Wang, H.; Lu, Z.; Yao, G.; Zeng, J.; Wan, Q.* “Interrupted Pummerer Reaction in Latent-Active Glycosylation: A Novel Type of Glycosyl Donors with Recyclable and Regenerative Leaving Group” Angew. Chem. Int. Ed. 2015, 54, 14432. (IF: 11.709).

·Highlighted by X-MOL:

4. Shu, P.; Zeng, J.; Tao, J.; Zhao, Y.; Yao, G.; Wan, Q.* “Selective S-deacetylation Inspired by Native Chemical Ligation: Practical Syntheses of Glycosyl Thiols and Drug Mercapto-analogues” Green Chem. 2015, 17, 2545. (IF: 8.506)

5. Wang, H.; Tao, J.; Cai, X.; Chen, W.; Zhao, Y.; Xu, Y.; Yao, W.; Zeng, J.; Wan, Q.* “Stereoselective Synthesis of α-linked 2-Deoxy Glycosides Enabled by Visible Light Mediated Reductive Deiodination” Chem. Eur. J. 2014, 20, 17319. (IF: 5.771)

·Highlighted by Photocatalysis:Wiley-VCH Hot Topics

6. Wan, Q.; Chen, J.; Yuan, Y.; Danishefsky, S. J.* “Oxo-ester Mediated Native Chemical Ligation: Concept and Applications” J. Am. Chem. Soc. 2008, 130, 15814. (IF: 13.038)

·Highlighted in Faculty of 1000 Biology 2009 (article ID 1147955)

7. Wan, Q.; Danishefsky, S. J.* “Free Radical Based, Specific Desulfurization of Cysteine: A Powerful Advance in the Synthesis of Polypeptides and Glycopolypeptides” Angew. Chem. 2007, 119, 9408; Angew. Chem. Int. Ed. 2007, 46, 9248. (IF: 11.709)

·Highlighted as a Very Important Paper (VIP)

·Highlighted in Angew. Chem. Int. Ed. 2008, 47, 1553.

Awards and Honors

2017         Asian Core Program Lectureship Award (to Taiwan)

2017         Asian Core Program Lectureship Award (to Singapore)

2016         National Natural Science Foundation of China (21672077)

2016         Wuhan Creative Talent Development Fund

2015         7th Asian Community of Glycoscience and Glycotechnology (ACGG) Conference Best Poster Award, Miyagi, Japan

2015         Natural Science Funds of Hubei Province for Distinguished Young Scholars

2014         National Natural Science Foundation of China (21472054)

2014         Open-end Research Fund of the State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

2012         “Thousand Talents Program” Young Investigator Award

2012         National Natural Science Foundation of China (21272082)

2012         the Specialized Research Fund for the Doctoral Program of Higher Education

2011         Amgen First Green Chemistry in Medicinal Chemistry Award

2006         Mr. and Mrs. Goodwin and Commonwealth Foundation for Cancer Research

2004         “Eiffel Scholarship” the French Ministry of Foreign Affairs and European Affairs.

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