Assoc. Professor

Phone: 027-83692745

Email: zengjing0052@hust.edu.cn

Academic Areas: Medicinal Chemistry

Research Interests: Carbohydrate chemistry and carbohydrate drug; Synthesis of bioactive natural products and clinical agents especially oligosaccharides and glycoconjugates.

Academic Degrees

PhD. in Organic Chemistry, 2013, Nanyang Technological University (NTU), Singapore
M.Sc. in Organic Synthesis, 2007, Xiamen University, Xiamen, China

B.Eng. in Chemistry and Chemical Engineering, 2004, Southeast University, Nanjing, China

Professional Experience

Assoc. Professor (2014-present); School of Pharmacy, HUST

Post-doc. (2013-2014); Nanyang Technological University (NTU), Singapore

Project Officer (2008-2009); Nanyang Technological University (NTU), Singapore

Synthesis Researcher (20070-2008) Shanghai ChemExplorer Company

Selected Publications

1.   Zeng J.; * Sun G.; Yao W.; Zhu Y.; Wang, R.; Cai, L.; Liu, K.; Zhang Q.; Liu, X.-W.; Wan, Q. * 2-Amino-deoxypyranoses in Glycosylation: Diversified Synthesis and Assembly in Oligosaccharides. Angew. Chem. Int. Ed. 2017, accepted.

2.   Zeng J.; Xu Y.; Wang, H.; Meng L.; Wan Q.* Recent Progress on the Synthesis of 2-Deoxy Glycosides. SCIENCE CHINA Chem., 2017, accepted.

3.  Ma, J.; Zeng, J.; Wan, Q.* “Postligation-Desulfurization: A General Approach for Chemical Protein Synthesis” Topics in Current Chemistry 2015, 363, 57 (invited, IF: 4.464).

4.  Zeng, J.#; Ma, J.#; Xiang, S.; Cai, S.; Liu, X. -W.* Stereoselective β-C-Glycosylation via Palladium-Catalyzed Decarboxylative Allylation: Formal Synthesis of Aspergillide A. Angew. Chem. Int. Ed., 2013, 52, 5134. (IF: 11.709) (Highlight in Synfacts 2013, 8, 870)

5.  Zeng, J.; Tan, Y. J.; Leow M. L.; Tirtorahardjo, D.; Liu, X. -W.* Facile Access to Cis-2,6-Disubstituted Ddihydrapyranes via Palladium Catalyzed Intramolecular Decarboxylative Allylation: Total Syntheses of (±)-Centrolobine, (+)-Decytospolide A and B. Chem. Eur. J. 2014, 20, 405. (IF: 5.771)

6.  Zeng, J.; Zhang, Q.; Zhang, H. K.*; Chen, A.* Synthesis of trans-Dihydroxybutyrolactols as Efficient 4C Building Blocks: Application to the Synthesis of Polyhydroxylated Alkaloids. RSC, Advances, 2013, 3, 20298. (IF: 3.840)

7.  Zeng, J.; Tan, Y. J.; Leow, M. L.; Liu, X. -W.* Copper(II)/Iron(III) Co-catalyzed Intermolecular Diamination of Alkynes: Facile Synthesis of Imidazopyridines. Org. Lett. 2012, 14, 4386. (IF: 6.364) (Highlight in Synfacts 2012, 8, 1300.)

8.  Zeng, J.; Bai, Y. G.; Ma, J. M.; Cai, S. T.; Liu, X. -W.*, Direct Synthesis of Pyrroles via A Silver Promoted Three-component Reaction Involving an Unsual Imidazole Ring Opening. Chem. Commun. 2011, 47, 12855. (IF: 6.834)

9.  Zeng, J.; Vedachalam, S.; Xiang, S. H., Liu, X. -W.*, Direct C-Glycosylation by Coupling of Organotrifluoroborates with Glycosyl Flouorides and Iits Application to The Total Synthesis of (+)-Varitriol. Org. Lett. 2011, 13, 42. (IF: 6. 6.732) (Highlighted in Organic Chemistry Portal, 2012, http://www.organic-chemistry.org /Highlights/2012/16January.shtm).

Courses Taught

Medicinal Chemistry and Experiments of Medicinal Chemistry

Advanced Organic Chemistry

Progress of Pharmaceutical Research

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