Main Courses
I. Organic Chemistry
Course name：Organic Chemistry (I)
Class hours/Credits：56/3.5
Lecturing hours:56.
Course description and goals:Organic chemistry is the chemistry of carbon compounds. It introduces pharmacy students to a few fundamental principles of organic chemistry and many extensions and applications of these principles, which are crucial to drug design, drug syntheses, structure-activity relationship analysis, and drug action. Organic chemistry I is a prerequisite for Organic Chemistry II (including Experimental Organic Chemistry).
Course name：Organic Chemistry (II)
Class hours/Credits：120/7.5
Lecturing hours: 80, Laboratory ours: 40
Course description and goals: Organic chemistry II follows Organic Chemistry I to form an integral course. Organic chemistry II consists of the theoretical part (12 chapters) and the experimental part (9 experiments). Completion of Organic Chemistry II is a prerequisite for major-specific core courses like Medicinal Chemistry, Natural Medicinal Chemistry, Pharmacology, Pharmaceutical Analysis, and Pharmaceutics.
II. Analytical Chemistry
Course name: Analytical Chemistry
Class hours/ Credits: 136 h / 8.5
Lecturing hours: 96 h; Laboratory hours: 40 h;
Course description and goals:Analytical chemistry is a basic course for pharmacy, biopharmaceutics, traditional Chinese medicine and other pharmacy majors. Through the study of this course, students are required to master the basic knowledge, basic theory and basic operation technology of chemical analysis and instrumental analysis.
III. Physical Chemistry
Course name: Physical Chemistry
Class hours/ Credits: 96 h / 6.0
Lecturing hours: 64 h; Laboratory hours: 32 h;
Course description and goals:Physical Chemistry is a foundational course at Tongji School of Pharmcy, HUST. It is a very broad subject, and plays an important role in the understanding of core theories in pharmaceutical sciences, particularly for pharmaceutics, physical organics, computational drug design and development, etc. This introductory course of physical chemistry includes laboratory practices and covers chemical thermodynamics and chemical kinetics.
IV. Biochemistry and Molecular Biology
Course name: Biochemistry
Class hours/ Credits: 120h/6.5
Lecturing hours: 72h; Laboratory hours: 42 h; Off-class hours: 6 h
Course description and goals: Biochemistry is the study of the structure and function of biological molecules such as proteins, nucleic acids, carbohydrates and lipids. Biochemistry is also used to describe techniques suited to understanding the interactions and functions of biological molecules. It is an important basic course in medical science. The task of studying biochemistry is to enable medical students to understand and master the normal functional and structural characteristics of biological molecules, and lay a necessary foundation for learning other basic and clinical medicine courses.
V.Medicinal Chemistry
Course name:Medicinal Chemistry
Class hours/ Credits: 104h/6.5
Lecturing hours: 72h; Laboratory hours: 32 h;
Course description and goals: Medicinal chemistry is the science that deals with the discovery or design of new therapeutic agents and their development into useful medicines. It is a chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences. It involves the discovery of new biologically active compounds, the construction of structure-activity relationships, the synthesis, and the study of their absorption, distribution, metabolism, and excretion (ADME), the interpretation of their mode of action at the molecular level.
VI. Pharmacognosy
Course name：Pharmacognosy
Class hours/Credits：104/6. 5
Lecturing hours：72；laboratory hours:32
Course description and goals: Pharmacognosy is one of the key courses in pharmacy science. It is an applied science that deals with the biological, biochemical and economic features of natural crude drugs and their active constituents. From botanical side, it concerned with the description & identification of drugs, both in whole state & in powder & with their history, commerce, collection, preparation and storage, which are of fundamental importance particularly for pharmacopoeial identification and quality control purposes. The main study task of the course is to characterize the pharmacology of crude extracts & active constituents, evaluate quality of Chinese medicines, and understand the interdisciplinary relationship with ethnobotany & ethnopharmacology. The aim of this course is to equip students with the knowledge in (i) authentication, identification, quality analysis, quality control and patenting of Chinese medicines (CMs); (ii) fundamental skills in research and development of Chinese medicinal products; and (iii) regulation and management of the pharmaceutical industry.
Basic contents and requirements
(1) Attitude：critical and serious, independent thinking, active learning
(2) Basic theory and knowledge: Organic Chemistry, Phytochemistry, Analytical Chemistry, Biochemistry, Pharmacology, Introduction of Traditional Chinese Medicine and Medicinal Botany.
(3) Basic skills：Morphology of medicinal plants in micro- and macro- view.
VII.Natural medicinal Chemistry
Course name：Natural Medicinal Chemistry
Class hours/Credits：112/7.0
Lecturing hours:64; Laboratory hours:48; Discussion class hours:10
Course description and goals: Natural Medicinal Chemistry is focused on the bioactive chemical components of natural products. The main content ofthis course contains the definition and classification of the structures,physical and chemical properties, extraction and isolation methods, identification methods, biosynthetic pathway,structural modification, structure-function relationships of the active compounds in the natural products. The purpose of the course is tocultivate students' ability to engage in the production and research of natural products. The course contains both a lecture and a laboratory component.
VIII.Pharmaceutical Analysis
Course name：Pharmaceutical Analysis
Class hours/Credits：112/7.0
Lecturing hours:72; Laboratory hours:40;
Course description and goals: Pharmaceutical analysis is a subject building on the experiment. The function of this course is to teach the students to build the view of comprehensive quality control of drugs, to make the students know the methods and technologies of pharmaceutical analysis, further to let the students do test works on the drug research, drug manufacture, drug supply, drug clinical usuage and drug market supervision, and to let the students have the ability of doing creative research and solving the problems of drug quality.
IX.Pharmacology
Course name：Pharmacology
Class hours/Credits：96/6.0
Lecturing hours:60; Laboratory hours:36;
Course description and goals: This course comprises of basic elements from pharmacokinetics and pharmacodynamics. For pharmacokinetic, the general pattern of the drug delivery shall be mastered by students; for pharmacodynamics, effects of drug on body or pathogen shall be understood. The drug mechanism, clinical indications, adverse reactions, and contraindication also need to be understood. For lab experiments, the perceptual knowledge shall be acquired from both of the drug actions and the basic studying methods of pharmacology research.
X.Pharmaceutics
Course name：Pharmaceutics
Class hours/Credits：136
Lecturing hours:72; Laboratory hours:64.
Course description and goals: Pharmaceutics is one of the main courses for pharmacy undergraduates. It is a comprehensive applied technology including basic theories, prescription design, preparation technology and quality control of dosage forms. Pharmaceutics is the scientific discipline concerned with the process of creating the dosage form (such as a pill for oral administration or a powder for intravenous injection) of a therapeutic that is to be used by patients. Put at its simplest-pharmaceutics converts a drug into a medicine.
The overall goals of this course include:
Explain the scientific principles in the design, preparation and evaluation of a variety of pharmaceutical dosage forms
Emphasize the mathematical tools needed for quantitative analysis of chemical kinetics, drug stability, and tissue drug Concentration-Time Profile.
Engage students in active learning such that they can successfully apply the fundamentals taught in this course to case studies involving specific formulation excipients, some example drugs and disease states.
XI.Biopharmaceutics and Pharmacokinetics
Course name：Biopharmaceutics and Pharmacokinetics
Class hours/Credits：96/6.0
Lecturing hours:45; Laboratory hours:32; Discussion class hours: 19.
Course description and goals: This course involves the fundamental study of the kinetics of drug absorption, distribution, metabolism and elimination (ADME). It is an introductory course to the basic principles and concepts of pharmacokinetics (PK) and the corresponding mathematical relationships. Students will calculate PK parameters from plasma and urine concentration data, interpret PK drug information, and use PK information to design or modify dosing regimens for individual patients. Major topics include the PK of IV bolus, oral dosing, IV infusion, multiple IV and oral dosing, multi-compartment models, hepatic and renal elimination, non-linear kinetics and therapeutic drug monitoring. The course is taught primarily in lecture format, with in-class and homework problem solving cases as appropriate. There will be an optional discussion session. This discussion session will provide an excellent opportunity for student’s to ask questions regarding lecture material and in-class/homework problem sets.
Course goals:
Define, explain, and differentiate fundamental principles and functionally dependent relationships of primary PK parameters.
Calculate common PK parameters from plasma and/or urine data after single and multiple IV or oral dosing administration.
Design appropriate dosing regimens based on population and patient specific PK information.
Predict effects of route and method of drug administration on plasma levels, using individual or population PK data, and recommend changes as needed.
Predict effects of drug interactions, disease states, and special populations on drug PK and modify dosage regimens appropriately.
XII.Pharmaceutical Administration
Course name:Pharmaceutical administration
Class hours/ Credits: 32 h / 2.0
Lecturing hours: 32 h; Laboratory hours: 0 h; Off - class hours: 0 h
Course description and goals: This course is a sub-discipline of the pharmaceutical sciences, which has the characteristics of a social science and use social, behavioral, administrative, economic, and legal sciences to study the influencing social factors and proper management system to ensure the quality of drug and pharmaceutical care and enhance the benign development of pharmacy business.
XIII.Clinical Pharmacotherapeutics
Course name:Clinical Pharmacotherapeutics
Class hours/ Credits: 48 h / 3.0
Lecturing hours: 48 h; Laboratory hours: 0 h; Off - class hours: 0 h
Course description and goals: This course focuses on core knowledge needed to understand the therapeutic use of drugs and develop appropriate, evidence-based treatment regimens across the lifespan. Basic principles of pharmacology, such as mechanisms of action, pharmacokinetics and pharmacodynamics, of major drug classes will be discussed in relation to physiology and pathophysiology; current research data and evidence-based treatment guidelines will be reviewed. Exemplars and case studies will be used for clinical application.
Course goals:
Analyze the pharmacological properties and general pharmacokinetic parameters of the most commonly used drugs in practice.
Compare the differences of drugs within categories including pharmacokinetic action, indication, dosages and side effects.
Evaluate indication for drug therapy for specific health problems.
Appraise appropriate monitoring parameters for drug effectiveness.
Evaluate special needs of obstetric, pediatric, adult, or gerontologic clients receiving drug therapy based on the needs of the individual.
